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Definition

A gene is a short piece of DNA. Genes tell the body how to build specific proteins. There are about 20,000 genes in each cell of the human body. Together, they make up the blueprint for the human body and how it works.

A person's genetic makeup is called a genotype.

Information

Genes are made of DNA. Strands of DNA make up part of your chromosomes. Chromosomes have matching pairs of 1 copy of a specific gene. The gene occurs in the same position on each chromosome.

Genetic traits, such as eye color, are dominant or recessive:

  • Dominant traits are controlled by 1 gene in the pair of chromosomes.
  • Recessive traits need both genes in the gene pair to work together.

Many personal characteristics, such as height, are determined by more than 1 gene. However, some diseases, such as sickle cell anemia, can be caused by a change in a single gene.

Gallery

Chromosomes and DNA
Humans typically have 23 pairs of chromosomes, or 46 chromosomes in total. Chromosomes are made up of long strands of DNA, which contain all the body's genes.

References

Gene. Taber's Medical Dictionary Online. www.tabers.com/tabersonline/view/Tabers-Dictionary/729952/all/gene. Accessed April 29, 2021.

Nussbaum RL, McInnes RR, Willard HF. The human genome: gene structure and function. In: Nussbaum RL, McInnes RR, Willard HF, eds. Thompson & Thompson Genetics in Medicine. 8th ed. Philadelphia, PA: Elsevier; 2016:chap 3.

Last reviewed May 3, 2021 by Linda J. Vorvick, MD, Clinical Associate Professor, Department of Family Medicine, UW Medicine, School of Medicine, University of Washington, Seattle, WA. Also reviewed by David Zieve, MD, MHA, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team..

Related specialties

Clinical Trials: Genes

UF Health research scientists make medicine better every day. They discover new ways to help people by running clinical trials. When you join a clinical trial, you can get advanced medical care. Sometimes years before it's available everywhere. You can also help make medicine better for everyone else. If you'd like to learn more about clinical trials, visit our clinical trials page. Or click one of the links below:

PD GENE

Development of a central repository for PD-related genomic data for future research.

Investigator
Irene A Malaty
Status
Accepting Candidates
Ages
18 Years - N/A
Sexes
All
View all genes studies

News and Patient Stories: Genes

More Genes stories

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