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Chronic obstructive pulmonary disease (COPD)

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UF Health Shands Hospital is rated by U.S. News & World Report as one of the nation's top hospitals for treating COPD.

Definition

Chronic obstructive pulmonary disease (COPD) is a common lung disease. Having COPD makes it hard to breathe.

There are two main forms of COPD:

  • Chronic bronchitis, which involves a long-term cough with mucus
  • Emphysema, which involves damage to the lungs over time

Most people with COPD have a combination of both conditions.

Patient Education Video: Chronic obstructive pulmonary disease

Smoking Myths & Facts Quiz

Cigarette smoking is the leading cause of COPD.

Answer:

The correct answer is fact. Smoking causes about 80% of all COPD cases. The more you smoke, the higher your risk of COPD. Other risk factors for COPD include secondhand smoke, pollution, or being exposed to certain fumes and gases at work.
Quitting smoking doesn't help once you have COPD.

Answer:

The correct answer is myth. There is no cure for COPD, but quitting smoking can help your lungs work better and lower your risk of dying from COPD. If you smoke, talk with your doctor about ways to quit.
Smoking both marijuana and tobacco increases your risk of COPD.

Answer:

The correct answer is fact. People who smoke both marijuana and tobacco have almost three times the risk of COPD compared with those who don't smoke. Experts aren't sure why, but they think smoking marijuana makes it easier for tobacco to damage the lungs.
Most people can quit smoking on the first try.

Answer:

The correct answer is myth. Most people try to quit about seven times before succeeding. Using quit smoking aids can help. These include counseling, prescription medicines, and nicotine patches, gum, lozenges, inhalers, and nasal spray -- some of which also require a prescription. Talk with your doctor about your options.
Smokers have more COPD flare-ups than nonsmokers.

Answer:

The correct answer is fact. Flares-ups are the most common reason that people with COPD have to go to the hospital. Having flare-ups causes your lungs to get worse more quickly. Call your doctor if your COPD symptoms get noticeably worse.
Men's lungs are more likely to be damaged by smoking than women's.

Answer:

The correct answer is myth. In fact, women's lungs are more likely to be damaged by smoking. This may be because of differences in genes or hormones. However, women who stop smoking get their lung function back more quickly than men. All smokers should try to quit. If you need help quitting, talk to your doctor.
Smoking is not addictive.

Answer:

The correct answer is myth. The nicotine in cigarettes and other tobacco products can cause the same kind of addiction as cocaine or heroin. When you smoke, the nicotine enters your lungs, gets absorbed into your bloodstream, and travels to your brain.
How you smoke can affect how much nicotine gets into your body.

Answer:

The correct answer is fact. You may take in more nicotine if you inhale deeply into the lungs and take a lot of puffs. This is because nicotine gets absorbed into your body through the lining of your mouth and as well as your lungs.
When you quit smoking, your heart rate and blood pressure return to normal levels.

Answer:

The correct answer is fact. Smoking raises your heart rate and blood pressure, and stopping helps them come back down. When you quit, you'll have less carbon monoxide in your blood, so it can carry more oxygen to your body. Your senses of taste and smell will improve.
Taking a puff of a cigarette can reduce your craving for more.

Answer:

The correct answer is myth. One puff of a cigarette will make your craving stronger. Instead, look for other ways to satisfy your craving, such as chewing sugarless gum or eating a piece of fruit or other low-calorie snack. Take walks or ride a bike. Exercise helps relieve the urge to smoke.

Alternative Names

COPD; Chronic obstructive airways disease; Chronic obstructive lung disease; Chronic bronchitis; Emphysema; Bronchitis - chronic

Causes

Smoking is the main cause of COPD. The more a person smokes, the more likely that person will develop COPD. But some people smoke for years and never get COPD.

If a person has a rare condition in which they lack a protein called alpha-1 antitrypsin, they can develop emphysema even without smoking.

Lungs
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.

Other risk factors for COPD are:

  • Exposure to certain gases or fumes in the workplace
  • Exposure to heavy amounts of secondhand smoke and pollution
  • Frequent use of a cooking fire without proper ventilation

Symptoms

Symptoms may include any of the following:

  • Cough, with or without mucus
  • Fatigue
  • Frequent respiratory infections
  • Shortness of breath (dyspnea) that gets worse with mild activity
  • Trouble catching one's breath
  • Wheezing

Because the symptoms develop slowly, many people may not know that they have COPD.

Exams and Tests

The best test for COPD is a lung function test called spirometry. This involves blowing out as hard as possible into a small machine that tests lung capacity. The results can be checked right away.

Spirometry
Spirometry is a painless study of air volume and flow rate within the lungs. Spirometry is frequently used to evaluate lung function in people with obstructive or restrictive lung diseases such as asthma or cystic fibrosis.

Using a stethoscope to listen to the lungs can also be helpful, showing prolonged expiratory time or wheezing. But sometimes, the lungs sound normal, even when a person has COPD.

Imaging tests of the lungs, such as x-rays and CT scans may be ordered. With an x-ray, the lungs may look normal, even when a person has COPD. A CT scan will almost always show signs of COPD if it is present.

Sometimes, a blood test called arterial blood gas may be done to measure the amounts of oxygen and carbon dioxide in the blood.

If your health care provider suspects you have alpha-1 antitrypsin deficiency, a blood test will likely be ordered to detect this condition.

Treatment

There is no cure for COPD. But there are many things you can do to relieve symptoms and keep the disease from getting worse.

If you smoke, now is the time to quit. This is the best way to slow lung damage.

Patient Education Video: Smoking tips to quit

Medicines used to treat COPD include:

  • Quick-relief drugs to help open the airways
  • Control drugs to reduce lung inflammation
  • Anti-inflammatory drugs to reduce swelling in the airways
  • Certain long-term antibiotics

In severe cases or during flare-ups, you may need to receive:

  • Steroids by mouth or through a vein (intravenously)
  • Bronchodilators through a nebulizer
  • Oxygen therapy
  • Assistance from a machine to help breathing by using a mask or through the use of an endotracheal tube

Your provider may prescribe antibiotics during symptom flare-ups, because an infection can make COPD worse.

You may need oxygen therapy at home if you have a low level of oxygen in your blood.

Pulmonary rehabilitation does not cure COPD. But it can teach you more about the disease, train you to breathe in a different way so you can stay active and feel better, and keep you functioning at the highest level possible.

LIVING WITH COPD

You can do things every day to keep COPD from getting worse, protect your lungs, and stay healthy.

Walk to build up strength:

  • Ask the provider or therapist how far to walk.
  • Slowly increase how far you walk.
  • Avoid talking if you get short of breath when you walk.
  • Use pursed lip breathing when you breathe out, to empty your lungs before the next breath.

Things you can do to make it easier for yourself around the home include:

  • Avoid very cold air or very hot weather
  • Make sure no one smokes in your home
  • Reduce air pollution by not using the fireplace and getting rid of other irritants
  • Manage stress and your mood
  • Use oxygen if prescribed for you

Eat healthy foods, including fish, poultry, and lean meat, as well as fruits and vegetables. If it is hard to keep your weight up, talk to a provider or dietitian about eating foods with more calories.

Surgery or other interventions may be used to treat COPD. Only a few people benefit from these surgical treatments:

  • One-way valves can be inserted with a bronchoscopy to help deflate parts of the lung that are hyperinflated (overinflated) in select patients.
  • Surgery to remove parts of the diseased lung, which can help less-diseased parts work better in some people with emphysema (lung volume reduction surgery).
  • Lung transplant for a small number of very severe cases.

Test Your Knowledge of COPD Triggers

People with COPD should take care to avoid getting a cold or the flu.

Answer:

The correct answer is true. Getting a cold or the flu can trigger a flare-up of symptoms. Reduce your risk of infection by washing your hands often and avoiding people with a cold or the flu. You should also get a flu vaccine each year and get a pneumococcal vaccine -- ask your doctor how often.
The air quality outside can affect your COPD symptoms.

Answer:

The correct answer is true. Pollution and other materials in the air can trigger COPD symptoms. You can check the air quality index (AQI) each day to see how clean the air is in your area. Look for the AQI posted in your local newspaper or on the TV or radio.
Secondhand smoke doesn't affect people with COPD.

Answer:

The correct answer is false. Secondhand smoke can trigger a flare-up of COPD symptoms. To limit your exposure, avoid places where people smoke. Also ask family and friends not to smoke near you or in or around your home.
Smoke from a wood-burning stove can trigger a flare-up.

Answer:

The correct answer is true. If you can't avoid using a wood-burning stove, choose one that is EPA-emission certified. Also, make sure to have the stove, fireplace, and chimney cleaned each year, and only burn wood that has been dry for many months.
Painting your living room can trigger COPD symptoms.

Answer:

The correct answer is true. Paint is just one household product that contains volatile organic compounds (VOCs). When inhaled, VOCs can cause your COPD symptoms to get worse. To limit your contact, use a fan to vent rooms when using paint or cleaning products.
You can reduce your exposure to pollen by:

Answer:

The correct answer is all of the above. Pollen is another possible trigger of COPD symptoms. Staying indoors when the pollen count is high helps prevent flare-ups. Pollen counts are highest between 5 AM and 10 AM on hot, dry, windy days. Remove indoor plants if they trigger symptoms.
You can keep mold out of your home by controlling moisture.

Answer:

The correct answer is true. Mold is another COPD trigger. It grows in places that are moist. Limit mold in your home by keeping the indoor humidity low. You can do this by using an air conditioner or dehumidifier.
Dust mites are common in dry areas of your home.

Answer:

The correct answer is false. Dust mites live in dust particles, but they thrive in humid locations. Dust mite droppings can trigger COPD. You can limit dust mites by dusting with a damp cloth, vacuuming often, washing bedding once a week in hot water, and using an air conditioner in warm weather.
Which of the following can cause a flare-up?

Answer:

The correct answer is all of the above. Pets can trigger COPD symptoms, but you don't have to get rid of your furry friend. Reduce your contact with triggers by keeping pets out of your bedroom and off of carpets, bed linens, and upholstered furniture. If possible, choose pets without fur or feathers.
Your appliances can cause indoor pollution.

Answer:

The correct answer is true. Any appliance that uses gas, oil, propane, natural gas, or kerosene can produce fumes that can trigger COPD symptoms. To reduce this risk, have your furnace and other heating and cooling systems cleaned and inspected each year.

Support Groups

You can ease the stress of illness by joining a support group. Sharing with others who have common experiences and problems can help you not feel alone.

Outlook (Prognosis)

COPD is a long-term (chronic) illness. The disease will get worse more quickly if you do not stop smoking.

If you have severe COPD, you will be short of breath with most activities. You may be admitted to the hospital more often.

Talk with your provider about breathing machines and end-of-life care as the disease progresses.

Possible Complications

With COPD, you may have other health problems such as:

  • Irregular heartbeat (arrhythmia)
  • Need for breathing machine support with a mask (non-invasive ventilation) and oxygen therapy
  • Right-sided heart failure or cor pulmonale (heart swelling and heart failure due to chronic lung disease)
  • Pneumonia
  • Collapsed lung (pneumothorax)
  • Severe weight loss and malnutrition
  • Thinning of the bones (osteoporosis)
  • Debilitation
  • Increased anxiety

When to Contact a Medical Professional

Go to the emergency room or call 911 or the local emergency number if you have a rapid increase in shortness of breath.

Prevention

Not smoking prevents most COPD. Ask your provider about quit-smoking programs. Medicines are also available to help you stop smoking.

Gallery

Spirometry
Spirometry is a painless study of air volume and flow rate within the lungs. Spirometry is frequently used to evaluate lung function in people with obstructive or restrictive lung diseases such as asthma or cystic fibrosis.
Lungs
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Lungs
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Quitting smoking
The many methods of quitting smoking include counseling and support groups, nicotine replacement therapy, prescription medications, and incremental reduction.
Lungs
The major features of the lungs include the bronchi, the bronchioles and the alveoli. The alveoli are the microscopic blood vessel-lined sacks in which oxygen and carbon dioxide gas are exchanged.
Coronavirus
Coronaviruses are a family of viruses. Infection with these viruses can cause mild to moderate respiratory illnesses such as the common cold. Some coronaviruses may cause severe illness and lead to pneumonia or even death.

References

Global Initiative for Chronic Obstructive Lung Disease (GOLD) website. Global Initiative for Chronic Obstructive Lung Disease: 2023 Report. goldcopd.org/2023-gold-report-2/. Accessed January 6, 2023.

Han MK, Lazarus SC. COPD: diagnosis and management. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 64.

National Institutes of Health, National Heart, Lung, and Blood Institute website. COPD national action plan. www.nhlbi.nih.gov/sites/default/files/media/docs/COPD%20National%20Action%20Plan%20508_0.pdf. Updated February 2021. Accessed July 13, 2022.

Rochester CL, Nici L. Pulmonary rehabilitation. In: Broaddus VC, Ernst JD, King TE, et al, eds. Murray and Nadel's Textbook of Respiratory Medicine. 7th ed. Philadelphia, PA: Elsevier; 2022:chap 139.

Last reviewed April 2, 2022 by Denis Hadjiliadis, MD, MHS, Paul F. Harron Jr. Associate Professor of Medicine, Pulmonary, Allergy, and Critical Care, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA. Also reviewed by David C. Dugdale, MD, Medical Director, Brenda Conaway, Editorial Director, and the A.D.A.M. Editorial team. Editorial update 01/06/2023..

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